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. This prompts the release of certain growth factors. When the platelet-rich plasma is injected into the desired treatment sites, skin tightening and rejuvenation are triggered., this treatment may be combined with other facial rejuvenation treatments. For example, if you’re looking to add volume to sunken, hollow cheeks, a PRP facelift may be followed with hyaluronic acid filler injections, such as Restylane or Juvederm.